Titlebook: Ovarian Cancer 3; Frank Sharp,Peter Mason,Jonathan Berek Book 1995 Chapman & Hall 1995 BRCA.TNF.cancer.cancer treatment.carcinoma.cell.cyt

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New insights into the genetics of human ovarian epithelial tumor development The actual mechanisms of tumorigenesis remain largely unknown in spite of these advances. Much of the difficulty comes from the complexity of the neoplastic phenotype itself. Indeed, this phenotype is not characterized by single, but by multiple abnormalities which can each vary in importance in in

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Growth factors and receptors in ovarian cancer) acting through its receptor (EGFR). In many tumour cells, it has been shown [1] that the role of EGF is taken by transforming growth factor-., (TGF-.,). In breast cancer, there is firm evidence that overexpression of EGFR is associated with poor prognosis [2], implying a role for this receptor in

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Activation of human ovarian cancer cells: role of lipid factors in ascitic fluidd epithelial cells of the skin and bowel. It has been estimated that 1 million cell divisions per second are required for the replacement of lost cells. The proliferation of normal cells is regulated by the action of a number of polypeptide and lipid factors called growth factors [1–8]. These growth

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Update on early ovarian cancer and cancer developing in benign ovarian tumorsd to early detection of this disease in the hope of improving survival. Very little is known, however, about the clinicopathological features of early ovarian cancer and whether early diagnosis and treatment will result in a major improvement in prognosis.