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MicroRNA in Human Cancer: One Step Forward in Diagnosis and Treatmentein-coding genes, and our knowledge on alterations of the functional noncoding sequences in cancer is largely absent. MicroRNAs (miRNAs) are ~22 nucleotide (nt) noncoding RNAs, which regulate gene expression in a sequence-specific manner via translational inhibition or mRNA degradation. Mounting evi

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Individualized Molecular Medicine: Linking Functional Proteomics to Select Therapeutics Targeting thcancers such as childhood leukemias, we have made remarkable progress to the point where survival is an expectation rather than a rarity. Although we do not have one panacea for all human cancers, 30 years later, we understand that each type of cancer and potentially each person’s cancer is differen