Titlebook: Organ Regeneration Based on Developmental Biology; Takashi Tsuji Book 2017 Springer Nature Singapore Pte Ltd. 2017 Organ regeneration.Orga

鋼筆尖

Functional Pituitary Tissue Formation Recapitulating Hypothalamus and Pituitary Development Using Eth non-neural head ectoderm and hypothalamic neuroectoderm in adjacent layers, followed by treatment with a Sonic Hedgehog agonist. Self-organization of Rathke’s pouch-like structures occurred at the interface of the two epithelia in vitro. Subsequently, various endocrine cells including corticotrop

mortuary

Inner Ear Organoids: Recapitulating Inner Ear Development in 3D Culture, of the inner ear responsible for detection of positional information. The potential applications of this system include investigation of inner ear development, disease modeling, drug screening, and therapy development. This chapter highlights the process of in vivo inner ear development, the ration

Inertia

Functional Tooth Regeneration,lacement. To realise the whole-tooth regeneration, we have developed a novel three-dimensional cell-manipulation method designated the ‘organ germ method’. This method involves compartmentalisation of epithelial and mesenchymal stem cells at a high cell density to replicate the epithelial-mesenchyma

復(fù)習(xí)

Coronary-Spasm

Functional Salivary Gland Regeneration, bioengineered salivary gland germs successfully engrafted grew in the transplantation site, generating the correct structure. The bioengineered salivary glands were able to secrete saliva into the oral cavity and improve dry mouth symptoms. In this chapter, we describe the recent progress and devel

競(jìng)選運(yùn)動(dòng)

Functional Lacrimal Gland Regeneration,ollicles has also been developed as a novel three-dimensional organ regeneration using stem cell manipulation—named the organ germ method. Recently, we successfully demonstrated fully functional bioengineered lacrimal gland replacements after transplanting a bioengineered organ germ. This study was

Cervical-Spine

Early Kidney Specification and Its Recapitulation by Pluripotent Stem Cells,sights have enabled the production of three-dimensional complex nephron structure from both mouse and human pluripotent stem cells, which would be a big progress toward the realization of kidney regenerative medicine.

倔強(qiáng)一點(diǎn)

Generation of Gastrointestinal Organoids Derived from Human Pluripotent Stem Cells,rated through a stepwise differentiation that largely mimics gastrointestinal development and is therefore a good system to study congenital defects of the human GI tract. Moreover, PSC-derived organoids are complex and contain mesodermal cell types comprising smooth muscle and subepithelial myofibr

ascetic

nostrum