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Molecular Models of Cancer Development,ication, loss of contact inhibition, invasiveness, and the ability to metastasize to distant organs. These malignant cells typically exhibit distinct phenotypes different from normal cells. Causes and metabolic pathways of oncogenesis and the influence of the environmental factors on cancer (Epigene

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Immune Surveillance and Cancer Pathogenesis,nce the first observation of spontaneous tumor regression in experimental animals. Current research on the neoplastic microenvironment has revealed the importance of the role of the host’s immune system in containing the neoplastic expansion. In particular, the pattern of immune cells infiltrating t