Titlebook: Optogenetics: A Roadmap; Albrecht Stroh Book 2018 Springer Science+Business Media, LLC, part of Springer Nature 2018 single cell electroph

Meditative

Cell Type-Specific Targeting Strategies for Optogenetics,tures. Optogenetic actuators are genetically encoded light-sensitive membrane proteins that can be selectively introduced into cellular circuits in the living brain using a variety of genetic approaches. Gene targeting approaches used in optogenetic studies vary greatly in their specificity, their s

diathermy

Molecular Engineering of Channelrhodopsins for Enhanced Control over the Nervous System, strength of optogenetic applications emerges directly from the unique properties of the utilized proteins. Consequently, modifying the properties of channelrhodopsins extends our research capabilities even further. In this chapter, I describe how targeted protein engineering results in enhanced opt

Emmenagogue

Optogenetic Control of Intracellular Signaling: Class II Opsins, are reviewed in previous chapters. Class II opsins are G-protein-coupled receptors (GPCR) and include the vertebrate opsins that underlie mammalian, including human, vision. Chimeras made of class II opsins and other GPCRs allow the precise control of secondary messengers of intracellular signaling

BANAL

Combining Optogenetics with MEA, Depth-Resolved LFPs and Assessing the Scope of Optogenetic Networkaneously. Optogenetics provides the toolbox to excite or inhibit a genetically defined subpopulation of neurons. Here, we present a detailed description of how to combine multi-electrode array (MEA) recording and optogenetics to study the role of parvalbumin positive interneurons in mouse somatosens

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調(diào)情

Two-Photon Optogenetics by Computer-Generated Holography, in neuroscience, especially for manipulating neuronal activity with optogenetics. The ability to selectively direct light in specific neurons expressing an optogenetic actuator, rather than in a large neuronal population within the microscope field of view, is now becoming attractive for studies th

Decline

CRAB

Employing Optogenetics in Memory Research,isms in over a hundred published projects. The incorporation of optogenetics enabled scientists to causally pinpoint the real-time roles of specific neuronal populations within the brain structures underlying memory, the functional connections between them, and the dynamics of memory representation

Encumber

Biomarker

Optogenetics: Lighting a Path from the Laboratory to the Clinic,s about neuronal circuitry that had previously been impossible or extremely difficult to test suddenly have become viable experimental questions. Although optogenetics was originally pioneered for use in neurons, it is now clear that systems as diverse as atrial cardiomyocytes, pancreatic islet cell