Titlebook: Opioids I; Albert Herz,Huda Akil,Eric J. Simon Book 1993 Springer-Verlag Berlin Heidelberg 1993 Biochemie.Biochemistry.Opiat.Opioid Peptid

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Opioid Receptor Multiplicity: Isolation, Purification, and Chemical Characterization of Binding Sitebinding sites, by isolating and purifying them. In order to do this with clarity it is necessary to present first some introductory comments about the different types of opioid receptors currently known, or at least postulated, and about their properties based on studies other than chemical isolatio

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Anatomical Distribution of Opioid Receptors in Mammalians: An Overviewof at least three receptor types, referred to as JI, 8, and K, and have distinct anatomical distributions (M. et al. 1987, 1988; S. and H. 1988; T. and Z. 1987), ligand selectivities (. and N. 1989; J. and G. 1984; R. et al. 1983), and functions in the brain and periphery (M. 1984; W. 1982). With th

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Opioid Receptor Regulationte of the NMD A receptor (for a review see Chap. 1). The three opioid receptors exhibit different ligand selectivities, strikingly different neuroanatomical patterns, distinct physiological and behavioral profiles, and differing sensitivities to naloxone (or naltrexone) antagonism. In the central ne

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Opioid Receptor-G Protein Interactions: Acute and Chronic Effects of Opioidsupied receptor with a guanine nucleotide binding protein (G protein). Accumulating evidence suggests that a similar mechanism is an essential component of κ-type opioid receptor function. In this chapter, we will discuss the evidence supporting these conclusions and review similarities and differenc

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Opioid Receptor-Coupled Second Messenger Systems of common properties, including general protein subunit structure, primary sequence homologies, and general gene structure and regulation. Receptors within each of these groups also share common effector systems and, in many cases, the effector systems themselves actually define the individual rece

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