Titlebook: Ontogeny and Phylogeny of the Vertebrate Heart; David Sedmera,Tobias Wang Book 2012 Springer Science+Business Media, LLC 2012 cardiovascul

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The Sarcoplasmic Reticulum in the Vertebrate Heart, E–C coupling links electrical excitation of the cardiomyocyte membrane to mechanical contraction. The fundamental principles of E–C coupling are highly conserved between vertebrate species, but important morphological and functional differences exist. The role of one organelle in particular, the sa

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Evolution of the Regulatory Control of the Vertebrate Heart: The Role of the Contractile Proteins,C). The activation of cTnC triggers a series of conformational changes through the components of the thin filament that results in the generation of force by the myocyte. While all cardiac contractions are powered by this mechanism, comparison of cardiac function between vertebrate species reveals s

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Ontogenesis of Myocardial Function,higher vertebrates. For simplicity, we distinguish three prenatal stages with different morphology, contraction mechanics, and conduction parameters: tubular heart, trabeculated one, and fully septated heart with coronary perfusion. Postnatal maturation involves namely quantitative changes and appea

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Basic Cardiac Development: The Heart and Its Electrical Components,body’s organs and relieving them of waste products. Although this description is instructive, it is in no way a reflection of the complex molecular processes that have gone into its correct development. This chapter sets out to present the reader with the very basics for understanding the one of the

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The Functional Significance of the Reptilian Heart: New Insights into an Old Question, cardiac shunts are under autonomic control and changes characteristically during the intermittent ventilation of the lungs. While cardiac shunts are detrimental to oxygen transport in the endothermic birds and mammals, the potential to control the amount of mixing of blood within the nonavian ventr