Titlebook: Oncodynamics: Effects of Cancer Cells on the Body; Gurmit Singh Book 2016 Springer International Publishing Switzerland 2016 cancer cells.

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The Disrupted Steady-State: Tipping the Balance in Favour of Cancer,nant cells with the potential for self-promoting growth and survival in the presence of anti-growth or pro-apoptotic signals. However, while these changes may initiate the process of cancer development, they are not necessarily sufficient for disease progression, given the body’s intrinsic ability t

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Cancer and Angiogenesis,elopment of blood vessels in tumours is modulated by pro- and anti-angiogenic factors. Pro-angiogenic factors include those that regulate remodelling of the extracellular matrix (ECM) and changes in perivascular cell structure, as well as those that promote endothelial cell changes and migration, in

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Cancer-Induced Inflammation,onset of cancer. Though much research since then has focused on inflammation-induced cancer, it is of equal importance to consider the impact tumour cells can have on the immune system. Stemming from the broader concept of “oncodynamics”, this chapter will discuss cancer-induced inflammation and imm

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Oncodynamic Effect of Cancer on Depression, dramatically increased. In addition to the psychosocial impact of a negative diagnosis, recent evidence suggests that cancer-induced depression (CID) is mediated by biological processes. This oncodynamic effect of cancer on the development of depression is poorly understood, leading to ineffective

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Oncodynamic Changes in Skeleton,d these . processes—how the bone changes in response to cancer cell invasion—it is necessary to define the types of cells that are present in normal bone, to explore the main physiological functions of these cells and of the bone itself, and to describe the types of cancers that often grow in bone.