| 書(shū)目名稱 | Ocular Transporters in Ophthalmic Diseases and Drug Delivery | | 編輯 | Joyce Tombran-Tink,Colin J. Barnstable | | 視頻video | http://file.papertrans.cn/701/700574/700574.mp4 | | 概述 | Focuses on the molecular characteristics, localization, and substrate specificities of several classes of well-known membrane transporters in various compartments of the eye.Illustrates how mutations | | 叢書(shū)名稱 | Ophthalmology Research | | 圖書(shū)封面 |  | | 描述 | Detection and responses to light are common features found throughout the plant and animal kingdoms. In most primitive life forms, a patch of light-sensitive cells make up a region containing a cell sheet devoid of any specialized anatomical structure. With the development of the eyes in more advanced life forms, light-sensing structures became more complex but primitive eyes are still in contiguity with other body tissues and fluids. The evolution of the eyeball promoted an increase in visual acuity and visual processing that, in turn, allowed vision to become the dominant sensory system for many species, including humans. The formation of a totally enclosed structure, however, required a unique set of solutions to enable the eye to control its environment. Like most organs, the eye evolved a series of homeostatic mechanisms to regulate its environment within tightly controlled limits. Unlike most organs, however, this advanced light-sensing structure has a series of requirements that place a tremendous burden on molecules that are responsible for controlling ocular homeostasis. There are many sig naling molecules and pathways that work in parallel or through crosstalk to maintain | | 出版日期 | Book 2008 | | 關(guān)鍵詞 | Biology; Diagnostics; Ocular; Therapeutics; Transporters; glycoprotein; molecular mechanisms; regulation | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-59745-375-2 | | isbn_softcover | 978-1-62703-865-2 | | isbn_ebook | 978-1-59745-375-2 | | copyright | Humana Press 2008 |
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