Titlebook: Occupational Cancers; Sisko Anttila,Paolo Boffetta Book 2020Latest edition Springer Nature Switzerland AG 2020 Cancer Epidemiology.Cancer

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Cancers of the Gastrointestinal Tract (Esophageal, Gastric, and Colorectal Cancer),nder a multifactorial etiology model for esophageal cancer (EC), with alcohol and tobacco drinking as the main risk factors for squamous cell variety in Western countries, and chronic gastroesophageal reflux for the adenocarcinoma. Certain occupations and occupational exposures such as dry cleaning

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Lung Cancer: Mechanisms of Carcinogenesis by Asbestos,e or multiplicative in the development of tumors. Research has indicated that some cellular and molecular events elicited by exposures to chemical carcinogens in cigarette smoke or asbestos fibers are different in lung epithelial cells, the target cells of lung carcinomas. We describe here contempor

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,Lung Cancer: Mechanisms and Markers—Carcinogens Other Than Asbestos,ns and require metabolic activation by cytochrome P450 (CYP) enzymes to exert their deleterious effects, including binding to DNA and formation of DNA adducts which, if not repaired, may lead to mutations in critical genes and cancer initiation. The induction of oxygen radical damage is considered t

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Lung Cancer: Genetic Susceptibility,lay a role in determining individual risk of developing lung cancer, the role of genetically determined host factors in occupational exposure-related lung cancer is poorly explored. Gene variants that might affect susceptibility to lung cancer fall into three categories: rare-risk, moderate-risk, an