| 書(shū)目名稱(chēng) | Nuclear Reprogramming and Stem Cells | | 編輯 | Justin Ainscough,Shinya Yamanaka,Takashi Tada | | 視頻video | http://file.papertrans.cn/669/668685/668685.mp4 | | 概述 | Provides a timely glimpse into the methods that have been developed over the last 50-60 years.Focuses on areas that have shown significant movement in recent years and are most likely to translate int | | 叢書(shū)名稱(chēng) | Stem Cell Biology and Regenerative Medicine | | 圖書(shū)封面 |  | | 描述 | .Research into the field of stem cell biology has developed exponentially over recent years, and is beginning to offer significant promise for unravelling the molecular basis of a multitude of disease states. Importantly, in addition to offering the opportunity to delve deeply into the mechanisms that drive disease aetiology the research is realistically opening the doors for development of targeted and personalized therapeutic applications that many considered, until recently, to be nothing more that a far fetched dream. This volume provides a timely glimpse into the methods that have been developed to instigate, and the mechanisms that have been identified to drive, the process of nuclear reprogramming, chronicling how the field has developed over the last 50-60 years..?.Since the early 1950s a small number of notable experiments have provided significant impetus to the field, primarily the demonstration of reprogramming ability, first by the complex cytoplasmic milieu that constitutes the amphibian egg, then that of the mammalian egg, and finally that of the mammalian embryonic stem cell. Most recently, the demonstration that a limited pool of defined molecules is capable of rep | | 出版日期 | Book 2012 | | 關(guān)鍵詞 | Ainscough; Cell; Nuclear; Reprogramming; Stem; Tada; Yamanaka | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-61779-225-0 | | isbn_softcover | 978-1-62703-904-8 | | isbn_ebook | 978-1-61779-225-0Series ISSN 2196-8985 Series E-ISSN 2196-8993 | | issn_series | 2196-8985 | | copyright | Springer Science+Business Media, LLC 2012 |
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