Titlebook: Nuclear Receptors; Current Concepts and Chris M. Bunce,Moray J. Campbell Book 2010 Springer Science+Business Media B.V. 2010 ATP.Metazoa.Vi

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Chris M. Bunce,Moray J. CampbellFocuses on biology of nuclear receptors.Up to date reviews of diverse aspects of Nuclear Receptor biology.Contributions from authors of major standing in the Nuclear Receptor Field.Provides an outstan

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What does Evolution Teach us about Nuclear Receptors?,riptional activity of NRs can be modulated. Finally, we argue that the evolutionary analysis of NRs has contributed to a conceptual shift of our understanding of nuclear receptors, from highly specific endocrine regulators to a promiscuous metabolic rheostat.

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Functions of Nuclear Receptors in Insect Development,fined critical roles for nuclear hormone receptors in controlling embryonic development, molting, metamorphosis, reproduction and metabolism. In this chapter, I review our understanding of the biological functions of all insect nuclear hormone receptors.

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Thyroid Hormone Receptors, factors. These receptors are particularly versatile since they also have the potential to mediate ligand-independent transcriptional control. Genetic analyses have revealed both specific and overlapping roles for each receptor, revealing how a small receptor family can mediate an extended range of biological functions.

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Systems Biology: Towards Realistic and Useful Models of Molecular Networks,systemic consequences of specific molecular perturbations. This chapter gives a brief overview of some of the approach in mathematical modeling of molecular networks. We choose to keep the mathematical detail minimal and highlight a number of concepts and approaches that are emerging in the analysis of molecular networks.

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