Titlebook: Novel Approaches to the Treatment of Alzheimer’s Disease; Edwin M. Meyer,James W. Simpkins,Jyunji Yamamoto Book 1989 Springer Science+Busi

Evolve

Delayed Matching-to-Sample in Monkeys as a Model for Learning and Memory Deficits: Role of Brain Nicxcept higher apes. In addition, spontaneous and conditioned behavior exhibited by the monkey is more similar to that of the human than any other laboratory animal.. Therefore, behavioral tasks which tap the higher cognitive abilities of these nonhuman primates may provide information more relevant t

輕浮思想

馬具

Potential Pharmacological Use of Neurotrophic Factors in the Treatment of Neurodegenerative Diseasesctors. These neurotrophic factors stimulate mechanisms necessary for survival, neurite growth and functions related to transmitter production and release. Nerve growth factor (NGF) is the first and best characterized neurotrophic factor and serves as a paradigm for more recently discovered molecules

Tractable

The Use of Reaggregating Cell Cultures And Immortalized Central Nervous System Cells to Study Cholinent and maintenance of neural connections is supported by neural trophic factors, trophic dysfunction represents one possible pathogenetic mechanism for such neurological and age-associated diseases. This laboratory has utilized primary reaggregating cell cultures and developed immortalized central

賄賂

Approaches to Gene Therapy in the CNS: Intracerebral Grafting of Fibroblasts Genetically Modified toease phenotypes ., an approach that has been named gene therapy (1). In an ideal gene therapy system, the new genetic information would be applied directly to the affected tissue. This direct approach has not yet been attempted, because the current methods of gene transfer are limited to replicating

放大

Exogenous Nerve Growth Factor Stimulates Choline Acetyltransferase Activity in Basal Forebrain of Ax maintenance in the adult (1,2). NGF has been found to have a similar role in the mammalian central nervous system (CNS) (3). NGF was first implicated in CNS function when Schwab et al. (4) found specific retrograde transport of exogenous NGF from cerebral and hippocampal cortices to neuronal cell b

不知疲倦

Neuronotrophic Factors, Gangliosides and Their Interaction: Implications in the Regulation of Nervou extrinsic factors. Like any living system, the nervous system represents a dynamic organization, whose various elements are in a continual state of change due to interactions not only with one another, but also with their extraneural environment. Neurons are exposed to such influences from cells wi

細(xì)菌等

Suppression of Active Neuronal Death by Immune Interferonically well characterized and of proven physiological significance (1). NGF is necessary for the survival and function of sympathetic and neural crest-derived sensory neurons. It is becoming clear that NGF is also important for the basal forebrain cholinergic neurons in CNS (2), a cell group involve

CAB

Basic Fibroblast Growth Factor, an Example of a Multifunctional Trophic Factor with Neurotrophic Act injury or during aging have been ascribed to deficiencies of trophic factors (1). For many years, the only known neurotrophic factor (NTF) was nerve growth factor (NGF). Studies with NGF have led to significant insights into neuronal cell biology and development, particularly in the peripheral nerv

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