Titlebook: Normal Pressure Hydrocephalus; Pathophysiology, Dia Ondrej Bradac Book 2023 The Editor(s) (if applicable) and The Author(s), under exclusiv

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CSF Physiologyspinal Fluid (CSF), watery fluid with a low concentration of protein and cellular components. CSF is mainly produced via plasma filtration and membrane secretion through choroid plexuses, a minority is secreted through secretion of ependymal surfaces of the cerebral ventricles and by the arachnoid l

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Genetic Aspects of iNPHsence of familial subtypes and new investigations of candidate genes suggest a genetic component to the pathogenesis. Whilst pedigree studies of iNPH provide the starting point for evidence of genetic risk factors, functional analysis of candidate genes and their mutations offers insight into possib

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Cognitive and Neuropsychiatric Features of Idiopathic Normal Pressure Hydrocephalusgether with gait disturbance and urinary incontinence, cognitive impairment constitutes a part of the clinical triad. Cognitive deficit is commonly accompanied by neuropsychiatric symptoms (NPS), observed in up to 85% of the patients. Both cognitive deficits and neuropsychiatric symptoms are thought

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