Titlebook: Nonmalignant Hematology; Expert Clinical Revi Syed A. Abutalib,Jean M. Connors,Margaret V. Ragni Book 2016 Springer International Publishin

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Sickle Cell Disease: Prevention of Complications. While giant strides in the prevention of pediatric morbidity and mortality have been made in the latter part of the twentieth century, adults with SCD are faced with a chronic, debilitating disease with limited preventive and therapeutic options. Stem cell transplantation, the only cure presently

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Anemia of Inflammation anemia of blood loss/iron deficiency (Cartwright and Lee 1971). It is an underproduction anemia characterized by a relatively low reticulocyte response for the degree of anemia. The traditional definition of the anemia of chronic disease was an anemia in the appropriate clinical setting with low se

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Iron Overload: Diagnosis, Complications, and Managementoses. Acquired iron overload is mainly due to multiple transfusions and to dyserythropoiesis. The damaging effect of iron excess concerns numerous organs and can therefore lead to miscellaneous clinical features, related especially to the liver, heart, pancreas, and rheumatological complications. Th

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Sideroblastic Anemias: Diagnosis and Managementevaluations (Fig. 1). The presence of this morphology is due to iron deposition in the mitochondria of the erythroid progenitor cells. Congenital SA may be due to one of several defined gene abnormalities or due to an as yet unknown defect (Bergmann et al. 2010). Acquired SA is caused by nutritional

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Platelet Disorders: Diagnostic Tests and Their InterpretationsBecause both thrombocytopenia and thrombocytosis can be associated with bleeding and with arterial and venous thrombosis, they engender substantial and appropriate concern by treating physicians. However, the number of circulating platelets in normal individuals is far in excess of the number requir

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Inherited Platelet Disorders: Diagnosis and Managementl procedures or trauma. They include patients who have decreased platelet counts, abnormal platelet function or a combination of both, in general reflecting underlying abnormalities that culminate in defective platelet production and function. Over the last two decades there has been an impressive i

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luation.? It covers the use of simulation in training in each specialty and is aimed at healthcare educators and administrators who are developing their own simulation centers or programs and professional organizations looking to incorporate the technology into their credentialing process.? For thos