Titlebook: Non-coding RNAs and Cancer; Muller Fabbri Book 2014 Springer Science+Business Media, LLC 2014 gene expression

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miRNAs as Cancer Biomarkers,r. In discussing miRNAs biomarkers in different cancers, we (1) provide evidence supporting the potential use of circulating (serum and plasma), urinary, salivary, and pleural effusion miRNAs as diagnostic markers, (2) discuss the advantages of their use, and (3) address challenges (e.g., validation

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MicroRNA SNPs in Cancer,nes or tumor suppressor genes. Whether a particular miRNA serves as either could almost be moot when the additional problems of SNPs enter the fray. A miRNA involved with SNPs (miR-SNPs) on any regulatory level, whether naturally cancer-inducing or not, could easily undergo an oncogenic transformati

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Bioinformatics Approaches to the Study of MicroRNAs,pigenomic variation and phenotypes to disease. These technologies are particularly well suited for discovery of both small RNAs, around 30–75 base pairs long, and long RNAs, longer than 75 base pairs, because the NGS sequencers can produce millions of short reads in a relatively rapid period of time

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Beyond miRNAs: Role of Other Noncoding RNAs in Cancer,arly, these new players have emerged as master regulators of multiple biological processes. One specific subset of ncRNAs, namely, microRNAs, received prevalent attention over the past decade, yet it forms only the tip of the iceberg. The noncoding RNA world is constantly expanding, whether it is by

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