Titlebook: Non-Protein Coding RNAs; Nils G. Walter (Associate Professor of Chemistry), Book 2009 Springer-Verlag Berlin Heidelberg 2009 Einzelmolekül

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RNA 3D Structural Motifs: Definition, Identification, Annotation, and Database Searching,ed RNAs are composed of recurrent modular motifs that play specific functional roles. Some motifs direct the folding of the RNA or stabilize the folded structure through tertiary interactions. Others bind ligands or proteins or catalyze chemical reactions. Therefore, it is desirable, starting from t

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The Small Ribozymes: Common and Diverse Features Observed Through the FRET Lens,e common reaction chemistry in cleaving their own backbone by phos-phodiester transfer, but are diverse in their secondary and tertiary structures, indicating that Nature has found at least five independent solutions to a common chemical task. Fluorescence resonance energy transfer (FRET) has been e

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Structure and Mechanism of the , Ribozyme,ides the basis of genetic regulation and depends upon glucosamine-6-phosphate (GlcN6P) as a coenzyme. Substantial biochemical and biophysical data relating to the structure and function of the . ribozyme has been amassed in a relatively short period of time since its discovery. A precise and compreh

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Group I Ribozymes as a Paradigm for RNA Folding and Evolution,versity of subtypes illustrates the modular character of RNA architecture and the potential for the evolution of new functions. The folding mechanisms of group I ribozymes illustrate the hierarchy of folding transitions and the importance of kinetic partitioning among competing folding pathways. Stu

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Group II Introns and Their Protein Collaborators,NAs, they require the assistance of proteins for efficient splicing in vivo. Proteins that facilitate splicing of organellar group II introns fall into two main categories: intron-encoded maturases and host-encoded proteins. This chapter will focus on the host proteins that group II introns recruite

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