Titlebook: Nitrates and Nitrate Tolerance in Angina Pectoris; M. Kaltenbach,G. Kober Conference proceedings 1983 Dr. Dietrich Steinkopff Verlag, GmbH

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Investigations to Demonstrate Nitrate Tolerance in Peripheral Vessels by Means of a Simple Hemodynamicacy during long-term nitrate therapy could be identified by means of a simple hemodynamic test possibly even suitable for use on an outpatient basis. We also attempted to answer the question of whether an eventual loss of drug efficacy was due to true tolerance development or was merely an apparent phenomenon in the context of adaptive changes.