Titlebook: Next Generation Sequencing in Cancer Research, Volume 2; From Basepairs to Be Wei Wu,Hani Choudhry Book 2015 Springer International Publish

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Mutational Similarities Across Cancers: Implications for Research, Diagnostics, and Personalized Thf histopathological tumor diagnostics is to determine the tumor’s anatomic origin and other morphological features that are the basis for selecting the appropriate therapy. Similarly, research programs are usually also focused on particular cancer entities. However, mutational tumor profiling perfor

合乎習(xí)俗

invulnerable

北極人

Next-Generation Sequencing for Cancer Biomarker Discovery,serve as valuable biomarkers for early detection, staging, and detailed molecular characterization of cancer for individualized therapy. Mutations in several known oncogenes (e.g., EGFR, HER2, KRAS) and tumor suppressor genes (e.g., TP53, PTEN, PI3K) are already being used as biomarkers to guide the

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acquisition

Clinical Applications of Next-Generation Sequencing of Formalin-Fixed Paraffin-Embedded Tumors, we review some of the recent developments in RNA and DNA sequencing from FFPE. We highlight some of the current challenges and considerations that must be in place before using NGS in a clinical setting. We begin with a discussion of the technical challenges in dealing with FFPE tumors, including n

PET-scan

CERE