Titlebook: New Strategies in Stroke Intervention; Ionic Transporters, Lucio Annunziato Book 2010 Humana Press 2010 brain damage.ionic homeostasis.isc

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,,,,,,,,n found in astrocytes and oligodendrocytes. In addition to its role in accumulation of Cl-, NKCC1 may also contribute to K+ clearance and maintenance of intracellular Na+ in glia. Recent studies suggest that NKCC1 activation leads to high [K+]o-induced astrocyte swelling and glutamate release as wel

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Role of TRPM7 in Ischemic CNS Injury,prevent DND coupled with their inability to provide neuroprotection in clinical trials has led our research groups to seek additional Ca. influx pathways in the hopes of identifying previously overlooked sources. Our recent studies have led to the demonstration of the important contribution of TRPM7

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Alexei Verkhratskysociate Partner bei Accenture. Er verfügt über langj?hrige.Industrieerfahrung (u. a. Gesch?ftsleitungsmitglied Roche Schweiz). Andreas Fibig ist Gesch?ftsführer der Pharmacia GmbH in Erlangen.978-3-409-12371-6978-3-322-87010-0

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Lucio Annunziato,Pasquale Molinaro,Agnese Secondo,Anna Pannaccione,Antonella Scorziello,Giuseppe Pig

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Mitochondrial Channels as Potential Targets for Pharmacological Strategies in Brain Ischemia,rial channels are involved in energy production, calcium handling, generation of reactive oxygen species (ROS) and cell-death related signaling, it is evident that increased understanding of these processes and their regulation will help the search for novel rational approaches to therapy.