Titlebook: New Psychoactive Substances; Pharmacology, Clinic Hans H. Maurer,Simon D. Brandt Book 2018 Springer Nature Switzerland AG 2018 New psychoac

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Self-Experiments with Psychoactive Substances: A Historical Perspective,erapists for more than a century. Scientifically inspired controlled SEs dominated until the end of the twentieth century, when ethical requirements minimized controlled SEs and “wild” SEs expanded particularly with the emergence of new psychoactive substances. The review focuses on laughing gas (ni

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Pharmacology of MDMA- and Amphetamine-Like New Psychoactive Substances, use. Detailed information about their psychotropic effects and health risks is often limited. At the same time, it emerged that the pharmacological profiles of these NPS resemble those of amphetamine or 3,4-methylenedioxymethamphetamine (MDMA). Amphetamine-like NPS induce psychostimulation and euph

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The Chemistry and Pharmacology of Synthetic Cannabinoid Receptor Agonist New Psychoactive Substance earliest SCRA NPS were simply repurposed from historical academic manuscripts or pharmaceutical patents describing cannabinoid ligands, recent examples bear hallmarks of rational design. SCRA NPS manufacturers have applied traditional medicinal chemistry strategies (such as molecular hybridization,

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1,2-Diarylethylamine- and Ketamine-Based New Psychoactive Substances,the late 1950s and early 1960s, when the pharmacological potential of this class was first realized. For example, hundreds of compounds have been pursued as part of legitimate research efforts to explore these agents. Some of these found their way out of the research labs and onto illicit markets of

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Synthetic Opioids,epidemic-level harms in some countries. According to the United Nations Office on Drugs and Crime, almost 12 million years were estimated loss of “healthy” life resulting in premature death and disability attributable to global opioid abuse just in 2015. Law enforcement and regulatory authorities ha