Titlebook: New Bacterial Vaccines; Book 2003

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Mucosal Immunity,f the entire immune system. Therefore, one may ask why there has not been a greater emphasis on developing vaccines that would elicit protection at the portal of entry of pathogens; the oral polio vaccine remains the only human mucosally delivered vaccine that has been widely adopted, although sever

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Group A , Vaccine Research,reduce the risk of transmission, and to prevent suppurative complications and post-streptococcal sequelae. The intent of this chapter is to provide a historical synopsis of GAS vaccine research, discuss recent advances in the field, and highlight prospects for the future. The reader is referred to r

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A Vaccine for Nontypable , ,Several lead candidate antigens have been proposed based on studies in animal models but have yet to be formulated for human trials. The composition of a vaccine requires that the antigens be conserved among strains, immunogenic and protective against infection and that the delivery of the vaccine r

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Vaccines for ,,rge number of factors. The overwhelming issues appear to encompass the wide variety of often redundant virulence factors that render ineffective approaches that target a single or even a few bacterial products; the antigenic and immunogenic properties of the major target of protective immunity, the

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