Titlebook: New Aspects for Treatment with Fosfomycin; Josef-Peter Guggenbichler Book 1987 Springer-Verlag/Wien 1987 absorption.antibiotic.antibiotics

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bsorption in a low dosage resulted in inadequate therapeutic results. The presently used parenteral administration in a dosage range of up to 250 mg/kg BW however allowed us to appreciate several unique properties of this drug which make it valuable in the treatment of serious bacterial infections.

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Summary,um in Mexico City in March 1986 presently available clinical and theoretical investigations were presented and indications for fosfomycin were established.The present booklet is a summary of representative papers presented at this meeting.

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Influence of Intracellularly Active Antibiotics (Fosfomycin, Rifampin, Sulfamethoxazole, Trimethoprportion to the extracellular drug concentration, RIF induced a significant drop both in chemiluminescence (18.3% at 50 mg/l) and O.?-generation (46.5% at 50 mg/l, p < 0.0005), which was reversible too. Chemotaxis was not influenced by neither of the agents and only RIF significantly reduced the rate

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Resistance of Intracellular Killing of Staphylococci by Macrophages as New Pathophysiologic Concept with β lactam antibiotics and among each other show a synergistic mode of action in broth and broth + addition of serum and granulocytes and are also able to eradicate these intracellularly surviving staphylococci..In a clinical study with 30 patients conservative treatment of acute hematogenous os