Titlebook: Neurovascular Events After Subarachnoid Hemorrhage; Towards Experimental Javier Fandino,Serge Marbacher,Emanuela Keller Book 2015 Springer

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Haemoglobin Scavenging After Subarachnoid Haemorrhageprove long-term outcome. Haemoglobin is avidly bound by haptoglobin, and the complex is cleared by CD163 expressed on the membrane surface of macrophages. We studied the kinetics of haemoglobin and haptoglobin in cerebrospinal fluid after SAH. We show that haemoglobin levels rise gradually after SAH

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Time-Dependent Changes in Cerebrospinal Fluid Metal Ions Following Aneurysm Subarachnoid Hemorrhage cerebral vasospasm. Currently, the underlying mechanisms are uncertain. Metal ions are important modulators of neuronal electrophysiological conduction and smooth muscle cell activity, thereby potentially contributing to vasospasm. We hypothesized that metal ion concentrations in the cerebrospinal

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Valproic Acid Treatment After Experimental Subarachnoid Hemorrhage possible neuroprotective drug in a prechiasmatic injection model of SAH in mice...: Mice were randomized to the following experimental groups: SAH, SAH?+?VPA, Sham, and Sham?+?VPA. VPA (400 mg/kg) or saline was administered within 30 min of SAH induction and every 12 h thereafter for 48 h. Neurobeh

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SAH-Induced MMP Activation and ,, Current Suppression is Mediated Via Both ROS-Dependent and ROS-Inde, we examined whether matrix metalloprotease (MMP) activation contributes to SAH-induced .. current suppression and cerebral artery constriction via activation of epidermal growth factor receptors (EGFRs). Using patch clamp electrophysiology, we observed that .. currents were selectively decreased

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