Titlebook: Neurotransmitter Enzymes; Alan A. Boulton,Glen B. Baker,Peter H. Yu Book 1986 Springer Science+Business Media New York 1986

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triptans

0893-2336 types of ligand-receptor binding, including chapters on general principles, drug discovery and development, and a most useful-appendix on computer programs for978-1-4899-4130-5978-1-59259-610-2Series ISSN 0893-2336 Series E-ISSN 1940-6045

嘲弄

Phenylalanine Hydroxylase, Tyrosine Hydroxylase, and Tryptophan Hydroxylase,.; .;.), the present chapter avoids unnecessary repetition of data already presented. Classical reaction mechanisms, kinetic properties, anatomical and histochemical analyses, and pharmacological studies on the reaction products, e.g., DOPA, dopamine, 5-hydroxytryptophan, and serotonin, are not incl

Bravura

Aromatic ,-Amino Acid Decarboxylase,nal status is unclear. In those tissues in which AADC is clearly functional, it is assumed the enzyme is present in massive excess relative to the activity of other monoamine enzymes. Thus, the prevailing concept has been that AADC is not rate-limiting in monoamine synthesis. The enzyme does not app

employor

BUOY

S-Adenosyl-L-Homocysteine Hydrolase,zyme in transmethylation reactions taking place in cells of the nervous system has also been examined (.), although no comprehensive treatment of this facet of AHH action exists Yet, information on brain AHH has been summarized (.) in a monograph devoted to the role of AdoMet in the CNS (.).

nocturia

Phenol Sulfotransferase,), as well as several neuropeptides including enkephalin (.) and cholecystokinin (.). As will be pointed out in greater detail below, sulfation of these endogenous compounds requires a common sulfate donor, 3′-phosphoadenosine-5′-phosphosulfate (PAPS), but is catalyzed by distinct forms of the enzym

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Book 1986 research in these fields. Similar reasons exist for Volume 4 on receptor binding techniques since experimental details are provided for all types of ligand-receptor binding, including chapters on general principles, drug discovery and development, and a most useful-appendix on computer programs for

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