Titlebook: Neurotoxicity of Metals; Michael Aschner,Lucio G. Costa Book 2017 Springer International Publishing AG 2017 neurotoxicity.metals.neurodege

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978-3-319-86800-4Springer International Publishing AG 2017

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Neurotoxicity of Metals978-3-319-60189-2Series ISSN 2190-5215 Series E-ISSN 2190-5223

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Inherited Disorders of Manganese Metabolismvides unique insights into disease pathobiology, and the discoveries of these three inherited disorders of manganese metabolism are already transforming our understanding of manganese homeostasis, detoxification, and neurotoxicity. Here, we review the mechanisms by which mutations in ., ., and . impact manganese homeostasis to cause human disease.

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Uranium and the Central Nervous System: What Should We Learn from Recent New Tools and Findings?f new technologies (omics and epigenetics) are of value in identifying new specific targets of uranium. Here we review the latest studies of neurogenesis, epigenetics, and metabolic dysfunctions and the identification of new biomarkers used to establish potential pathophysiological states of neurodevelopmental and neurodegenerative diseases.

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