Titlebook: Neuroscience in the 21st Century; From Basic to Clinic Donald W. Pfaff,Nora D. Volkow Reference work 20162nd edition Springer Science+Busin

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Adult Neurogenesisrogenesis critically contributes to hippocampal function, allowing life-long adaptation processes. If adult neurogenesis fails, this might contribute to several important diseases, including dementias, major depression and schizophrenia, as well as temporal lobe epilepsy.

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Dendritic Elaboration: Morphology and Chemistry – involving the summation of signals as well as spatial – entailing the aggregation of excitatory and inhibitory inputs from individual branches. Dendrites were thought to convey electrical signals passively. However, as shown recently dendrites can activly support action potentials and release neu

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Regressive Phenomena: Refining Connectionsy of the guidance cues that instructed neurons to their target initially also regulate regressive events later in development. Beyond the removal of supernumerary connections, regressive processes also allow for the creation of a number of complex synaptic structures and the refinement of individual

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Dendritic Morphology and Functionl and electrical compartments and the implications for synaptic integration and plasticity will be reviewed. In addition, this chapter will review different forms of dendritic computation and its implication in synaptic plasticity and in the hierarchical processing of information in the cerebral cor

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Cell Biology of the Synapse PSD displays a complex array of proteins, which are arranged in a hierarchical manner: (1) receptors, ion channels, and adhesion proteins shared with the postsynaptic membrane; (2) scaffold proteins connecting the receptors to each other, to other membrane components, and to the actin cytoskeleton;

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