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Titlebook: Neuroprotective Therapy for Stroke and Ischemic Disease; Paul A. Lapchak,John H. Zhang Book 2017 Springer International Publishing Switzer

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發(fā)表于 2025-3-21 16:39:27 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書(shū)目名稱(chēng)Neuroprotective Therapy for Stroke and Ischemic Disease
編輯Paul A. Lapchak,John H. Zhang
視頻videohttp://file.papertrans.cn/665/664380/664380.mp4
概述Multifaceted discussion of stroke neuroprotection--from its history to models, research, and clinical relevance.Focuses on new and developing treatments, including combination therapies, for stroke di
叢書(shū)名稱(chēng)Springer Series in Translational Stroke Research
圖書(shū)封面Titlebook: Neuroprotective Therapy for Stroke and Ischemic Disease;  Paul A. Lapchak,John H. Zhang Book 2017 Springer International Publishing Switzer
描述A critical and comprehensive look at current state-of-the-art scientific and translational research being conducted internationally, in academia and industry, to address new ways to provide effective treatment to victims of ischemic and hemorrhagic stroke and other ischemic diseases. Currently stroke can be successfully treated through the administration of a thrombolytic, but the therapeutic window is short and many patients are not able to receive treatment. Only about 30% of patients are "cured" by available treatments. In 5 sections, the proposed volume will explore historical and novel neuroprotection mechanisms and targets, new and combination therapies, as well as clinical trial design for some of the recent bench-side research.
出版日期Book 2017
關(guān)鍵詞CNS disorders; thrombolysis; oxidative stress; excitotoxicity; sex-specific
版次1
doihttps://doi.org/10.1007/978-3-319-45345-3
isbn_softcover978-3-319-83272-2
isbn_ebook978-3-319-45345-3Series ISSN 2363-958X Series E-ISSN 2363-9598
issn_series 2363-958X
copyrightSpringer International Publishing Switzerland 2017
The information of publication is updating

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Nitrones, Old Fellows for New Therapies in Ischemic Stroketherapeutic strategy. Regarding the intrinsic complexity of ischemic stroke, pleiotropy has been proposed as a key issue, and nitrones, known to act as radical traps, have arisen as interesting drug candidates. From its widely known antioxidant behavior, new mechanisms of action have been proposed b
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Neuroprotective Strategies via Modulation of Innate Immune Receptorsthe ischemic neuroinflammatory response or the resulting ischemic brain damage. The role of the PRRs in ischemic stroke is discussed as well as the ways to modulate these pathways with the aim to develop successful future stroke therapies.
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Harnessing the Power of the Human Immune System via Multi-omic Immune Profiling in Stroke Treatment is being created, and will ultimately change the way we diagnosis and treat stroke patients. This review will briefly outline current approaches and how to leverage these discoveries to achieve person-centered stroke care.
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