Titlebook: Neurophysiological Techniques; Basic Methods and Co Alan A. Boulton,Glen B. Baker,Case H. Vanderwolf Book 1990 Springer Science+Business Me

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Multisite Optical Measurement of Membrane Potential, changes in three types of optical signals: absorption, birefringence, and fluorescence. This screening effort has resulted in the discovery of dyes with a signal-to-noise ratio 100 times larger than was available from any signal in 1971. Several of these dyes (., e.g., .) have been used to monitor

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Book 1990 pot- tials. Humphrey and Schmidt offer a thoughtful review of the uses and limitations of the technique of recording extracellular unit potentials in the brain. Hoffer presents an introduction to a field that is of great interest but is technically very difficult-the reco- ing from cells and axons

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Whole-Cell and Microelectrode Voltage Clamp,. However, as Hodgkin and Huxley (1952) taught us long ago, analysis of the mechanisms that generate electrical activity is far easier with voltage clamp. If the behavior of ion channels depends on voltage, the first step in studying such channels is to control the voltage. Under voltage clamp, the

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In Vivo Voltammetry,are, for example, at least seven postulated 5-hydroxytryptamine (5-HT) receptors and associated subtypes. Such studies involve biochemical measurement of changes in second messenger systems, behavioral tests of receptor function or measurement of physiological responses produced by receptor activati

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