Titlebook: Neuropharmacology of Ethanol; New Approaches Roger E. Meyer,Michael J. Lewis,Steven M. Paul Book 1991 Springer Science+Business Media New Y

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Ethanol and Rewarding Brain Stimulation,When a substance is repeatedly used it is reasonable to assume that in some way its use is reinforcing. It may be that it is necessary for life, it has a taste or smell worth seeking, or its use may lead to acceptance by peers. During periods of depression or anxiety, self-administration of an abused substance may relieve anxiety or depression.

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Ethanol and the GABAA Receptor-Gated Chloride Ion Channel, (Liljequist and Engel, 1984) and in certain behavioral paradigms, the development of cross tolerance and cross dependence (Boisse and Okamoto, 1980; Le et al., 1986). These findings suggest that ethanol, barbiturates and benzodiazepines may share at least one common mechanism of action.

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