Titlebook: Neuronal Network Dynamics in 2D and 3D in vitro Neuroengineered Systems; Monica Frega Book 2016 The Editor(s) (if applicable) and The Auth

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Introduction,Bi-dimensional networks of dissociated neurons developing in vitro and coupled to Micro-Electrode Arrays devices (MEAs) represent a valid experimental model for studying the universal mechanisms governing the formation and conservation of neuronal cell assemblies (Marom and Shahaf in Q Rev Biophys 35(1):63–87, .).