Titlebook: Neuroendocrine Neoplasia Management; New Approaches for D Giordano Beretta,Alfredo Berruti,Orlando Goletti Book 2021 Springer Nature Switze

LUDE

New Concepts in Pathologyct of the tumor cells and their proliferative activity in terms of the number of mitoses or proliferation index (Ki-67)..In PanNENs, for example, Ki-67 labeling index correlates significantly with overall survival and also with disease progression in patients with advanced neoplasms and with tumor r

BRUNT

東西

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New Approaches in Medical Therapiesnhibitors (pazopanib, cabozantinib, lenvatinib, axitinib, surufatinib). Moreover, immune checkpoint inhibitors have also been investigated in NETs, with some encouraging results in well-differentiated tumors, especially for lung NETs. Clinical studies have also investigated the efficacy of epigeneti

frozen-shoulder

Locoregional Therapies of NEN On the other hand, liver ablation, firstly introduced for percutaneous imaging-guided approach and more recently also applied in open and laparoscopic setting, can provide eradication of liver metastases with less invasiveness than traditional surgery. Moreover, due to the high rate of relapse afte

Arb853

NETs of the Lungin receptors (SSTRs). Systemic chemotherapy is reserved for those cases of locally advanced or metastatic disease, even if the standard regimen has not yet been defined. The role of targeted therapies in LCs remains still limited with the exception of the only approved drug (everolimus) in clinical

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LEER

Treatment of Pancreatic Neuroendocrine TumorsRRT) are all adequately supported by strong scientific data, and there are no clear criteria that favor the choice of one treatment over the other. The decision-making process should be conducted as part of a multidisciplinary tumor board and must be based on some key elements: the Grade (G 1,2,3),

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