| 書目名稱 | Neurodegeneration in Multiple Sclerosis | | 編輯 | Massimo Filippi,Marco Rovaris,Giancarlo Comi | | 視頻video | http://file.papertrans.cn/664/663972/663972.mp4 | | 概述 | The application of modern quantitative MR techniques is changing dramatically our understanding of how MS causes irreversible disability.These techniques evidence that MS is not only a white matter di | | 叢書名稱 | Topics in Neuroscience | | 圖書封面 |  | | 描述 | .In multiple sclerosis (MS), conventional magnetic resonance imaging (cMRI) has proved to be a valuable tool to increase diagnostic confidence and for monitoring the efficacy of experimental treatment. However, cMRI has limited specificity and accuracy of cMRI to the most disabling aspects of the MS pathology, known to occur in and outside macroscopic lesions. Modern quantitative MR techniques have the potential to overcome the limitations of cMRI, and their application is changing dramatically our understanding of how MS causes irreversible disability. In detail, there is an increasing body of MR evidence that MS is not only a white matter disease and does not only cause focal lesions, as well as that neurodegeneration is an important aspect of the disease (since the earliest clinical phases), which is only partially related to inflammatory changes. There is also increasing perception that modern MR methodologies should be more extensively employed in clinical trials to derive innovative information...Written by world-renowned scientists, the volume provides a state-of-the-art on the most recent MRI techniques related to MS, and it will bi and indispensable tool for all those work | | 出版日期 | Book 2007 | | 關(guān)鍵詞 | Alzheimer; Alzheimer’s disease; Expanded Disability Status Scale; brain; magnetization trasfer ratio; neu | | 版次 | 1 | | doi | https://doi.org/10.1007/978-88-470-0391-0 | | isbn_softcover | 978-88-470-5583-4 | | isbn_ebook | 978-88-470-0391-0 | | copyright | Springer-Verlag Milan 2007 |
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