| 書目名稱 | Neural Transplantation in Cerebellar Ataxia |
| 編輯 | Lazaros C. Triarhou |
| 視頻video | http://file.papertrans.cn/664/663757/663757.mp4 |
| 叢書名稱 | Neuroscience Intelligence Unit |
| 圖書封面 |  |
| 描述 | erebellar ataxia is a failure in muscular coordination that re- C sults from a slow, progressive deterioration of neurons in the cerebellum. An estimated 150,000 people are affected by the he- reditary ataxias and related disorders in the United States. At present, there is no known cure. In an experimental treatment aimed at reconstructing the damaged pathway through exog- enous neuronal supplementation, genetically ataxic mice have been used for intracerebral grafting of genetically healthy cerebellar neuroblasts, and evidence has been obtained for graft-induced en- hancement of behavioral responses after bilateral cerebellar grafts. Such results are encouraging and underscore the potential of the neural grafting technique in restoring cerebellar function. How- ever, many of the pathological and biochemical mechanisms in the interaction between grafted tissue and the host brain need to be further elucidated in extensive experimental studies, and great cau- tion must be used in contemplating the theoretical feasibility of a possible application in humans. |
| 出版日期 | Book 1997 |
| 關(guān)鍵詞 | experiment; health; neurobiology; research |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-662-22213-3 |
| isbn_softcover | 978-3-662-22215-7 |
| isbn_ebook | 978-3-662-22213-3Series ISSN 1431-0406 |
| issn_series | 1431-0406 |
| copyright | Springer-Verlag Berlin Heidelberg 1997 |
|Archiver|手機(jī)版|小黑屋|
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