Titlebook: Neoplastic Diseases of the Blood; Peter H. Wiernik,John M. Goldman,Robert A. Kyle Book 20135th edition Springer Science+Business Media New

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Molecular Biology and Cytogenetics of Chronic Lymphocytic Leukemia of more effective mitogens, initially tetradecanoyl phorbol acetate (TPA) [2], then CD40 ligand [3], and most recently CpG oligonucleotides combined with Interleukin 2 [4, 5], metaphases can be obtained in the majority of cases of CLL and clonal abnormalities are identifiable in approximately 80 % [6].