Titlebook: Naturally Occurring Antibodies (NAbs); Hans U. Lutz Book 2012 The Editor(s) (if applicable) and The Author(s), under exclusive license to

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https://doi.org/10.1007/978-1-4614-3461-0Antibodies; Lutz; NAbs; Naturally; Occuring

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978-1-4939-5331-8The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines

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Hans U. LutzComprehensive in scope.With contributions by international experts.Illustrates the functional properties of NAbs

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Naturally Occurring IgM Antibodies to Oxidation-Specific Epitopest invading pathogens, as well as in tissue homeostasis by mediating the clearance of cellular debris. This latter recognition of self by NAbs was often thought to reflect the polyreactivity of low affinity antibodies. The finding that oxidation-specific epitopes are dominant targets of naturally occ

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Naturally Occurring Antibodies Directed Against Carbohydrate Tumor Antigensof tumor-associated antigens. In closer scrutiny of their nature, some of these antibodies could be defined as naturally occurring antibodies due to the germline configuration of the variable immunoglobulin region. The majority of these immunoglobulins recognize carbohydrate antigens which can be cl

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Naturally Occurring Autoantibodies in Mediating Clearance of Senescent Red Blood Cellsste in animals with 3 germ layers. Such NAbs became a necessity to selectively clear aged red blood cells (RBC) surviving 60 to 120 d in higher vertebrates. IgG NAbs to senescent RBC are directed to the most abundant integral membrane protein, the anion-transport protein or band 3 protein, but only