| 書目名稱 | Natural Resistance to Tumors and Viruses | | 編輯 | Otto Haller | | 視頻video | http://file.papertrans.cn/662/661914/661914.mp4 | | 叢書名稱 | Current Topics in Microbiology and Immunology | | 圖書封面 |  | | 描述 | Natural resistance is now coming to be recognized as a potentially important phenomenon in host defense against infection and ma- lignancy. Genetically controlled resistance mechanisms are usUally effective early in infection and before conventional immune responses are generated. Comparisons of experimental systems where natural resistance plays a prominent role demon- strate the complexities of the host defense mechanisms involved, as evidenced in the present volume. Nevertheless, some com- mon components of genetic resistance are discernible and largely comprise natural killer cells, macrophages, and interferon These and additional factors would seem to constitute a first line of de- fense in host resistance against both viruses and tumors. It is evi- dent that considerable variation in the relative importance of di- stinct mechanisms may be found among various resistance sy- stems and that, most likely, additional effector functions will be discovered. Resistance to tumors and most viruses is under polygenic control, has a complex mode of inheritance, and depends on appro- priately complex effector mechanisms. Instances, however, whe- re a single gene locus determines resistanc | | 出版日期 | Book 1981 | | 關(guān)鍵詞 | Killer cells; Resistance; interferon; interferon research; macrophages | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-642-68069-4 | | isbn_softcover | 978-3-642-68071-7 | | isbn_ebook | 978-3-642-68069-4Series ISSN 0070-217X Series E-ISSN 2196-9965 | | issn_series | 0070-217X | | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE |
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