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Titlebook: Natural Product-based Synthetic Drug Molecules in Alzheimer‘s Disease; Therapeutic & Theran Abha Sharma,Gyan Prakash Modi Book 2023 The Edi

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發(fā)表于 2025-3-21 16:25:05 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書(shū)目名稱Natural Product-based Synthetic Drug Molecules in Alzheimer‘s Disease
副標(biāo)題Therapeutic & Theran
編輯Abha Sharma,Gyan Prakash Modi
視頻videohttp://file.papertrans.cn/662/661888/661888.mp4
概述Examines natural products as source of novel drug against Alzheimer’s disease.Covers the role of metal homeostasis and oxidative stress in the pathogenesis of Alzheimer’s disease.Discusses the role of
圖書(shū)封面Titlebook: Natural Product-based Synthetic Drug Molecules in Alzheimer‘s Disease; Therapeutic & Theran Abha Sharma,Gyan Prakash Modi Book 2023 The Edi
描述This book illustrates the importance of natural products as the source for the development of novel drugs for the treatment of neurodegenerative disorders, including Alzheimer‘s disease. It also highlights the role of reactive oxygen species and altered metal homeostasis in the progression of Alzheimer’s disease and examines the potential of antioxidants and anti-chelating agents in the clinical intervention of neurodegenerative diseases. The book also discusses the role of neuroinflammation in the pathogenesis of Alzheimer’s disease. The chapters provide information about the drug targets, progress in the development of natural product-based therapeutics, biomarkers, fluorescent diagnostic tools, and theranostic for Alzheimer‘s disease. The book also provides information about the design and synthesis of natural product-based derivatives against the various targets of Alzheimer‘s disease including epigenetic targets and the metal dyshomeostasis hypothesis. Cutting across different disciplines, this book is a valuable source for neuroscientists, chemical biologists, pharmaceutical researchers, and synthetic biologists..
出版日期Book 2023
關(guān)鍵詞Alzheimer’s disease; Antioxidant; Natural molecules; Biomarkers; Multi-target ligand
版次1
doihttps://doi.org/10.1007/978-981-99-6038-5
isbn_softcover978-981-99-6040-8
isbn_ebook978-981-99-6038-5
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapor
The information of publication is updating

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Oxidative Stress and Metals in Alzheimer’s Diseasefects the elderly population. Key pathological hallmarks of AD are extracellular depositions of beta-amyloid plaques, intracellular accumulation of neurofibrillary tangles (NFTs), and alterations in amyloid precursor protein (APP) gene, and it is clinically characterised by changes in cellular and m
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Neuroinflammation in Alzheimer’s Diseaseelderly individuals. Mild-to-severe extent of neurodegeneration triggers AD in most cases. Patients with AD carry a higher chance of generation of dementia, memory loss, and gradual loss of basic intellect. According to a recent report, calcium dysfunction at the neuron level and microglia-mediated
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Approved Cholinesterase Inhibitor-Based Derivatives: Synthesis and Their Biological Evaluationchers. Alzheimer’s disease (AD) is one such disease that involves multiple largely ambiguous pathophysiological pathways, which makes it a challenging thrust area of research around the globe. The current approved drugs for the management of the disease include rivastigmine, donepezil, galantamine (
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Polyphenol: Development of Polyphenol-Inspired Derivatives Targeting Pathological Factors of ADs. Polyphenolic compounds, a class of natural plant compounds, have been extensively studied for their potential therapeutic use in AD. The neuroprotective, antioxidant, as well as anti-inflammatory properties exhibited by these compounds are important in the treatment and management of AD. Phenolic
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