Titlebook: Natural Killer Cell Protocols; Cellular and Molecul Kerry S. Campbell,Marco Colonna Book 20001st edition Humana Press 2000

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Fluorogenic Substrates as Detectors of Caspase Activity During Natural Killer Cell-Induced Apoptosin and granzymes A and B), the other requiring ligation of CD95 on target cells with CD95 (APO-1/Fas) ligand on the effector cell (.–.). Both processes lead to target cell apoptosis and lysis (.). Perforin and granzymes A (and B) have been implicated as main contributors to membrane and/or nuclear di

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Generation of Antibodies to Cell Surface Markers on Mature Natural Killer Cells,n when monoclonal antibodies (MAbs) have been generated, they do not always react with a given receptor from all strains of mice. For example, 5E6 binds to Ly49C and/or I from B6, C3H, and NZB strains, but fails to react with any NK cells of 129, C57BR, C58, or FVB mice. Besides Ly49 receptors, NKR-

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