Titlebook: Natural Compounds as Drugs, Volume I; Frank Petersen,René Amstutz Book 2008 Birkh?user Basel 2008 chemical space.drug research.enzymes.hig

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Progress in Drug Researchhttp://image.papertrans.cn/n/image/661689.jpg

貞潔

https://doi.org/10.1007/978-3-7643-8117-2chemical space; drug research; enzymes; high throughput screening; natural product; screening

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Birkh?user Basel 2008

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amnesia

Frank Petersen,René AmstutzHighlights innovative opportunities in drug discovery.Overview of strategies and screening methods.Compilation of current applicable technology.Includes supplementary material:

Pelago

Strain improvement for production of pharmaceuticals and other microbial metabolites by fermentatioology, recombinant DNA technology, and genetics. The progress in strain improvement has increased fermentation productivity and decreased costs tremendously. These genetic programs also serve other goals such as the elimination of undesirable products or analogs, discovery of new antibiotics, and deciphering of biosynthetic pathways.

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,Mother Nature’s gifts to diseases of man: the impact of natural products on anti-infective, antichof past, present and future agents, in general only considering compounds currently in clinical Phase II or later, that were/are derived from nature’s chemical skeletons. Finishing with a discussion of the current and evolving role(s) of microbes (bacteria and fungi) in the production of old and new agents ostensibly produced by higher organisms.

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Collision

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0071-786X ogy.Includes supplementary material: The use of herbal medicines, their preparation and application in human therapy, was described for the first time in history by the Sumerians approximately 5000 years ago. Even earlier in India and China, a highly sophisticated medical system with plant-based the