Titlebook: Nanotoxicology in Nanobiomedicine; PK Gupta Textbook 2023 The Editor(s) (if applicable) and The Author(s), under exclusive license to Spri

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Introduction and Historical Background,iomedicine is now being used to help treat diseases and prevent health-related problems. In brief, the prefix “nano” is a Greek word which means “dwarf.” The word “nano” means very small or miniature size. This chapter deals with basic information related to nano, an overview of historical developme

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Mechanism of Nanotoxicity,al activities of nanoparticles (NPs) and their products to determine whether and to what extent they may pose a threat to the environment and human health, and defined as the study of the nature and mechanism of toxic effects of nanoscale materials/particles on living organisms and other biological

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Organ and Non-organ-Directed Nanotoxicity,rticles (NPs) find their way easily to enter the human body and cross the various biological barriers and may reach the most sensitive organs. On the basis of available experimental models, it may be difficult to judge their toxicity. NPs may interfere with the normal physiological mechanisms of the

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Nanotoxicity: Health and Safety Strategies, a challenge for companies and regulators to ensure the development of safe and effective products for consumers. With regard to a general testing approach for human health hazard evaluation of NPs, a first step to determine potency may include a prioritization-related in vitro screening strategy to

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Nano-Based Drug Delivery Systems,In addition to being vehicles for drug delivery, NPs can be used as pharmaceuticals as well as diagnostics. Most of these are proteins and peptides, and their delivery present special challenges. Cell and gene therapies are sophisticated methods of delivery of therapeutics. Recently, advances in tar

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