| 書目名稱 | N-Acetylaspartate | | 副標(biāo)題 | A Unique Neuronal Mo | | 編輯 | John R. Moffett,Suzannah B. Tieman,Aryan M. A. Nam | | 視頻video | http://file.papertrans.cn/661/660005/660005.mp4 | | 概述 | Covers topics that both researchers and clinicians have interest in.Includes supplementary material: | | 圖書封面 |  | | 描述 | .N-acetylaspartate, or NAA, is the acetylated form of the amino acid aspartate, and it is present exclusively in the nervous system. Indeed, NAA is one of the most highly concentrated chemicals found in the brain of humans and animals, and yet the functions served by this brain-specific metabolite remain elusive, and controversial. Despite the uncertainties surrounding the functions of NAA in the development and operation of the nervous system, this molecule has attracted the attention of researchers and clinicians for two distinct reasons. ..First, the acetyl proton on NAA gives off a very prominent signal in water-suppressed, proton magnetic resonance spectroscopy (MRS), which permits clinicians to monitor levels of NAA in the brains of patients in a non-invasive manner. Because NAA is found primarily in neurons, and because the levels in the brain have been found to change rapidly after injury, or slowly during neurodegenerative diseases, MRS has become a preferred method of analyzing nerve cell dysfunction and death without surgical intervention. ..The second reason that NAA has attracted attention in recent years is that a congenital genetic disorder of NAA metabolism has been | | 出版日期 | Conference proceedings 2006 | | 關(guān)鍵詞 | Alzheimer; ELIZA; Nervous System; attention; neurobiology; neurons | | 版次 | 1 | | doi | https://doi.org/10.1007/0-387-30172-0 | | isbn_softcover | 978-1-4899-8888-1 | | isbn_ebook | 978-0-387-30172-3 | | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines |
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