| 書(shū)目名稱(chēng) | Muscle Atrophy | | 編輯 | Junjie Xiao | | 視頻video | http://file.papertrans.cn/642/641398/641398.mp4 | | 概述 | Describes the general aspects of muscle atrophy.Overviews molecular mechanisms of muscle atrophy.Provides diagnosis, treatment strategies, promising agents and future prospects of muscle atrophy | | 叢書(shū)名稱(chēng) | Advances in Experimental Medicine and Biology | | 圖書(shū)封面 |  | | 描述 | .The book addresses the development of muscle atrophy, which can be caused by denervation, disuse, excessive fasting, aging, and a variety of diseases including heart failure, chronic kidney diseases and cancers. Muscle atrophy reduces quality of life and increases morbidity and mortality worldwide. The book is divided into five parts, the first of which describes the general aspects of muscle atrophy including its characteristics, related economic and health burdens, and the current clinical therapy. Secondly, basic aspects of muscle atrophy including the composition, structure and function of skeletal muscle, muscle changes in response to atrophy, and experimental models are summarized. Thirdly, the book reviews the molecular mechanisms of muscle atrophy, including protein degradation and synthesis pathways, noncoding RNAs, inflammatory signaling, oxidative stress, mitochondria signaling, etc. Fourthly, it highlights the pathophysiological mechanisms of muscle atrophy in aging and disease. The book’s fifth and final part covers the diagnosis, treatment strategies, promising agents and future prospects of muscle atrophy. The book will appeal to a broad readership including scienti | | 出版日期 | Book 2018 | | 關(guān)鍵詞 | Muscle atrophy; Muscle wasting; Skeletal muscle; Mitochondria signaling; Noncoding RNAs | | 版次 | 1 | | doi | https://doi.org/10.1007/978-981-13-1435-3 | | isbn_ebook | 978-981-13-1435-3Series ISSN 0065-2598 Series E-ISSN 2214-8019 | | issn_series | 0065-2598 | | copyright | Springer Nature Singapore Pte Ltd. 2018 |
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