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Titlebook: Molecular mechanisms and physiology of disease; Implications for Epi Nilanjana Maulik,Tom Karagiannis Book 2014 Springer Science+Business M

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書目名稱Molecular mechanisms and physiology of disease
副標(biāo)題Implications for Epi
編輯Nilanjana Maulik,Tom Karagiannis
視頻videohttp://file.papertrans.cn/639/638616/638616.mp4
概述Includes chapters written by leading experts in the field.Examines major diseases (cardiovascular disease, respiratory disease, diabetes, cancer) from a molecular and physiological perspective.Include
圖書封面Titlebook: Molecular mechanisms and physiology of disease; Implications for Epi Nilanjana Maulik,Tom Karagiannis Book 2014 Springer Science+Business M
描述.In a simplified form, epigenetics refers to heritable changes in phenotype that are not due to changes in the underlying DNA sequence. In this book, epigenetic mechanisms of regulation and dysregulation in health and disease are explored in great depth. Detailed chapters on epigenetic processes including DNA methylation and chromatin post-translational modifications including potential interventions with DNA methyltransferase inhibitors and histone deacetylase inhibitors are explored in initial chapters. These provide a detailed overview and important background to the entire field. The book is then focussed on epigenetic mechanisms involved in various diseases including anti-inflammatory and autoimmune conditions. Important accounts relating to the effects of epigenetics in metabolic syndrome, cardiovascular disease and asthma are the focus of subsequent chapters. The role of epigenetic dysregulation in malignancy is a current topic of interest and represents an intense field of research. A large component of this book is dedicated to the analysis of aberrant epigenetic processes in carcinogenesis and cancer progression. Further, chapters are focused on emerging cancer prevention
出版日期Book 2014
關(guān)鍵詞DNA methylation; developmental origins of disease; histone acetylation; histone methylation; molecular m
版次1
doihttps://doi.org/10.1007/978-1-4939-0706-9
isbn_softcover978-1-4939-4623-5
isbn_ebook978-1-4939-0706-9
copyrightSpringer Science+Business Media New York 2014
The information of publication is updating

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978-1-4939-4623-5Springer Science+Business Media New York 2014
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https://doi.org/10.1007/978-1-4939-0706-9DNA methylation; developmental origins of disease; histone acetylation; histone methylation; molecular m
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ncer) from a molecular and physiological perspective.Include.In a simplified form, epigenetics refers to heritable changes in phenotype that are not due to changes in the underlying DNA sequence. In this book, epigenetic mechanisms of regulation and dysregulation in health and disease are explored i
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,Holding Hands: Toddlers’ Imaginary Peer Play, consistent transformative action that involves entering and sharing imaginary situations, coordinated actions and joyful bodily communication. Future research should further explore the influence of peer relations on expanding imagination and on promoting collaborative learning interactions instigated by toddlers.
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