| 書目名稱 | Molecular Basis for Mitochondrial Signaling | | 編輯 | Tatiana K. Rostovtseva | | 視頻video | http://file.papertrans.cn/639/638024/638024.mp4 | | 概述 | Covers advanced studies of structure, function, and regulation of the unique family of mitochondrial channels and transporters.Describes the current understanding of the mitochondria’s role in cellula | | 叢書名稱 | Biological and Medical Physics, Biomedical Engineering | | 圖書封面 |  | | 描述 | This book covers recent advances in the study of structure, function, and regulation of metabolite, protein and ion translocating channels, and transporters in mitochondria. A wide array of cutting-edge methods are covered, ranging from electrophysiology and cell biology to bioinformatics, as well as structural, systems, and computational biology. At last, the molecular identity of two important channels in the mitochondrial inner membrane, the mitochondrial calcium uniporter and the mitochondrial permeability transition pore have been established. After years of work on the physiology and structure of VDAC channels in the mitochondrial outer membrane, there have been multiple discoveries on VDAC permeation and regulation by cytosolic proteins. Recent breakthroughs in structural studies of the mitochondrial cholesterol translocator reveal a set of novel unexpected features and provide essential clues for defining therapeutic strategies. .Molecular Basis for Mitochondrial Signaling. covers these and many more recent studies of mitochondria function, their communication with other organelles, and their critical roles in development, aging, and in a plethora of stressful or degenerati | | 出版日期 | Book 2017 | | 關(guān)鍵詞 | Biophysics of membrane transport; Calcium signaling; Cellular metabolism; Ion channels and transporters | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-319-55539-3 | | isbn_softcover | 978-3-319-85688-9 | | isbn_ebook | 978-3-319-55539-3Series ISSN 1618-7210 Series E-ISSN 2197-5647 | | issn_series | 1618-7210 | | copyright | Springer International Publishing AG 2017 |
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