| 書目名稱 | Molecular Aspects of the Stress Response: Chaperones, Membranes and Networks | | 編輯 | Peter Csermely,László Vígh | | 視頻video | http://file.papertrans.cn/639/638016/638016.mp4 | | 概述 | Chapter Summaries.Detailed Illustrations | | 叢書名稱 | Advances in Experimental Medicine and Biology | | 圖書封面 |  | | 描述 | We are extremely happy to present the reader this book containing a summary of a well-known research field, the phenomenon of cellular stress defense from two new angles: networks and membranes. The volume starts with an introduction to the concept of molecular chaperones in their original sense: R. John Ellis, the founder of the chaperone concept describes chaperones as mediators of correct assembly and/or misassembly of other macromolecular complexes. This sets the tone of the book, where later chapters give detailed examples of the richness of chaperone ac- tion by hundreds of other proteins and membrane structures. The reader will learn the role of chaperone classes such as Hsp27 or Hsp90, the action of highly organized chaperone networks in various cellular compartments such as the ER or mitochondrial/ER networks as well as the molecular details of the signaling mechanisms leading to chaperone induction during stress. Various special stress defense mechanisms against oxidative stress or dryness will also be covered. Membranes comprise a surprising mixture of stability and dynamics in the cell. Their role in the regulation of the stress response has been accepted only slowly in | | 出版日期 | Book 2007 | | 關(guān)鍵詞 | Activation; Chaperone; Chaperones; Csermely; Lipid; Organelle; Response; Stress; regulation | | 版次 | 1 | | doi | https://doi.org/10.1007/978-0-387-39975-1 | | isbn_softcover | 978-1-4419-2297-7 | | isbn_ebook | 978-0-387-39975-1Series ISSN 0065-2598 Series E-ISSN 2214-8019 | | issn_series | 0065-2598 | | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines |
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