| 書目名稱 | Molecular Aspects of Oxidative Drug Metabolizing Enzymes |
| 副標(biāo)題 | Their Significance i |
| 編輯 | Emel Arin?,John B. Schenkman,Ernest Hodgson |
| 視頻video | http://file.papertrans.cn/639/638013/638013.mp4 |
| 叢書名稱 | Nato ASI Subseries H: |
| 圖書封面 |  |
| 描述 | Presented here are recent advances in biochemical, toxicological, and regulatory aspects of oxidative drug metabolizing enzymes. Mainly cytochrome P450-dependent and flavin-containing monooxygenases (FMO) are covered. Moreover, the book deals with genotoxicity studies and toxicological interactions of environmental chemicals and mechanisms of mutagenicity and tumor formation. The construction of genetically engineered mammalian cells for the production of a specific P450 isozyme and the application of these cell lines in drug metabolism, mutagenicity and toxicity studies are described in detail. Further, insight is provided into how a number of aquatic species cope with pollutants and their genotoxicity. |
| 出版日期 | Conference proceedings 1995 |
| 關(guān)鍵詞 | Oxidation; biology; carcinogenesis; cell; cell culture; cytochrome P450; drug; enzyme; enzymes; metabolism; mo |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-642-79528-2 |
| isbn_softcover | 978-3-642-79530-5 |
| isbn_ebook | 978-3-642-79528-2Series ISSN 1010-8793 |
| issn_series | 1010-8793 |
| copyright | Springer-Verlag Berlin Heidelberg 1995 |
|Archiver|手機(jī)版|小黑屋|
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