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Evaluation of Drug-Induced Liver Injuries (DILI) with Human Hepatocytes: Scientific Rationale and Exhes based on the .ey .diosyncratic .eterminant (KID) hypothesis—that drugs with KID are likely to cause idiosyncratic drug toxicity. We have identified that metabolism-dependent toxicity and induction of reactive oxygen species as two important KIDs. In vitro experimental approaches with primary cul

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