Titlebook: Microbial Reagents in Organic Synthesis; Stefano Servi Book 1992 Springer Science+Business Media Dordrecht 1992 Amino acid.Monosaccharid.O

Admonish

effrontery

A Building Block Strategy for Asymmetric Synthesis: The DHAP-Aldolasesoadly applicable enzymic catalysts for use in asymmetric synthesis. Made readily available by recombinant DNA methodology and being remarkably stable, these enzymes are capable of promoting efficient, highly enantio- and diastereocontrolled C-C bond formations of a type that proves useful in the . s

充足

豎琴

Acyloin Formation Mediated by Benzoylformate Decarboxylasespiophenone. The reaction was stereoselective, with (S)-2-hydroxypropiophenone being produced in enantiomeric excesses ranging from 91% to > 98%. The biocatalyst responsible for these condensations was identified as benzoylformate decarboxylase by demonstration that the PAGE purified enzyme catalysed

cornucopia

Prognosis

geometrician

New Enzymatic Methods for the Selective Functionalization of Carbohydrate Derivativesynthesis of enantiomerically enriched monosaccharides and to establish new enzymatic techniques for the chemo- and regioselective functionalization of carbohydrates, peptides and complex glycoconjugates. The pheromone (+)-.-brevicomin was synthesized by a chemoenzymatic chiral pool synthesis from ca

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Efficient Synthesis of Optically Active Carbohydrates and Other Oxygenated Compounds Through Bio-Oxie cis-diols, in the fermentation broth. These diols serve as excellent chiral pool synthons and can be easily manipulated through simple synthetic procedures to a variety of oxygenated natural products. Further stereoselective manipulations of the enantiomerically pure arene cis-diols permit efficie

syring

Chemoenzymatic Synthesis of Natural Products and Bioactive Compoundsin only one of their possible chiral forms. Also, the configuration of molecules (natural or unnatural) is very important in their biological function. Asymmetric synthesis is a primary focus of activity in organic chemistry and enzymes offer a convenient alternative to conventional reagents as a me

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Biotransformations Applied to the Synthesis of Vitamins and Pharmaceuticalscur. Various biotransformation have successfully been employed in order to redesign natural products in their nature-identical form or to synthesize certain pharmaceuticals. In most cases, the aim of using a biotransformations is to introduce chirality into a molecule, to achieve a regioselective fu