Titlebook: Microbial Cyclic Di-Nucleotide Signaling; Shan-Ho Chou,Nicolas Guiliani,Ute R?mling Book 2020 Springer Nature Switzerland AG 2020 Microbio

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Detection of Cyclic Dinucleotide Binding Proteins In response to stimuli, activated dinucleotide cyclases synthesize cyclic dinucleotides. Once made, cyclic dinucleotides bind macromolecule receptors, including proteins and RNA, to allosterically regulate downstream functions. Many important classes of cyclic di-GMP protein receptors have been ide

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Osmoregulation via Cyclic di-AMP Signalingriboswitch receptors. Cyclic di-AMP has been found to impact on a wide array of cellular processes including resistance to acid, heat, antibiotics, osmolarity changes and connected to central metabolism, peptidoglycan homeostasis, virulence, biofilm formation, immunomodulation, sporulation, DNA repa

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Measuring Individual Cell Cyclic di-GMP: Identifying Population Diversity and Cyclic di-GMP Heteroges in the measurement of real time cyclic di-GMP levels in single cells have uncovered significant dynamic heterogeneity of second messenger concentrations within bacterial populations. This heterogeneity results in a wide range of phenotypic outcomes within a single population, providing the potenti

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tide turnover proteins and receptors.Reports on the populati.This book explores the broad and diverse biological and physiological impacts of established and newly discovered cyclic di-nucleotide second messenger signaling systems, while also providing descriptions of the intriguing biochemical char